Eine Methode zur Darstellung Tritium-markierter cancerogener polycyclischer Kohlenwasserstoffe mit extrem hoher spezifischer Aktivität
1966; De Gruyter; Volume: 21; Issue: 9 Linguagem: Inglês
10.1515/znb-1966-0910
ISSN1865-7117
AutoresHans Emmerich, Peter Schmialek,
Tópico(s)Synthesis and Biological Evaluation
ResumoA method is described for the preparation of tritiated polycyclic aromatic hydrocarbons with extremely high specific activity in the presence of AlCl 3 and HTO. The hydrocarbons are purified by preparative thin layer and paper chromatography. The radiochemical purity of the compounds was proved by paper chromatography and dilution analysis. The following specific activities are reached: Anthracene: 54 Curies/mMol, 7,12-Dimethylbenzanthracene: 19 Curies/mMol, 3,4-Benzopyrene: 24 Curies/mMol, and 3-Methylcholanthrene: 44 Curies/mMol.
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