Use of cystatin C determination in clinical diagnostics.
2003; National Institutes of Health; Volume: 147; Issue: 2 Linguagem: Inglês
Autores
Jan Mareš, David Stejskal, J. Vavrouskova, Karel Urbánek, Roman Herzig, Petr Hluštı́k,
Tópico(s)Folate and B Vitamins Research
ResumoThis paper presents a current view of the possible clinical uses of cystatin C determination. Cystatin C is an inhibitor of cysteine proteases, and relatively stable in the systemic circulation it is comparatively easily determined. Although in clinical practice it is known primarily as a relatively reliable and endogenous marker for glomerular filtration, lately cystatin C analysis has been discussed in connection with the diagnostics of a variety of diseases such as early atherosclerosis, Alzheimer's dementia, vascular aneurysms, hyperhomocysteinaemia and other neurodegenerative diseases.
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