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YADAMP: yet another database of antimicrobial peptides

2012; Elsevier BV; Volume: 39; Issue: 4 Linguagem: Inglês

10.1016/j.ijantimicag.2011.12.003

1872-7913

Stefano Piotto, Lucia Sessa, Simona Concilio, Pio Iannelli,

Protein Hydrolysis and Bioactive Peptides

This work presents an antimicrobial peptide database (YADAMP) based on an extensive literature search. This database is focused primarily on bacteria, with detailed information for 2133 peptides active against bacteria. YADAMP was created to facilitate access to critical information on antimicrobial peptides (AMPs). The main difference between YADAMP and other web databases of AMPs is the explicit presence of antimicrobial activity against the most common bacterial strains. YADAMP allows complex queries, easily accessible through a web interface. Peptide information can be retrieved based on peptide name, number of amino acids, net charge, hydrophobic percentage, sequence motif, structure and activity against bacteria. YADAMP is suitable for reviewing information on AMPs and for structure–function analyses of peptides. The database can be accessed via a web-based browser at http://www.yadamp.unisa.it.