A Common Mutation in the Defensin DEFB126 Causes Impaired Sperm Function and Subfertility
2011; American Association for the Advancement of Science; Volume: 3; Issue: 92 Linguagem: Inglês
10.1126/scitranslmed.3002289
ISSN1946-6242
AutoresTheodore L. Tollner, Scott A. Venners, Edward J. Hollox, Ashley I. Yudin, Xue Liu, Genfu Tang, Houxun Xing, Robert J. Kays, Tsang Lau, James W. Overstreet, Xiping Xu, Charles Bevins, Gary N. Cherr,
Tópico(s)Plant Reproductive Biology
ResumoA frequent frameshift mutation in defensin DEFB126 , a protein that adheres to the surface of human sperm, weakens its ability to penetrate cervical mucus-like gels and causes low fertility.
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