Artigo Acesso aberto Revisado por pares

Region of Difference 1 in Nontuberculous Mycobacterium Species Adds a Phylogenetic and Taxonomical Character

2009; American Society for Microbiology; Volume: 191; Issue: 18 Linguagem: Inglês

10.1128/jb.00683-09

ISSN

1098-5530

Autores

Jakko van Ingen, Rina de Zwaan, Richard Dekhuijzen, Martin J. Boeree, Dick van Soolingen,

Tópico(s)

Diagnosis and treatment of tuberculosis

Resumo

The esat-6 and cfp-10 genes are essential for virulence in Mycobacterium tuberculosis. Among nontuberculous mycobacteria, we found these genes only in M. kansasii, M. szulgai, M. marinum, and M. riyadhense, with unique sequences. This adds a phylogenetic and taxonomical characteristic and may represent a virulence factor for nontuberculous mycobacteria.

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