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The health-related quality of life burden of co-morbid cardiovascular disease and major depressive disorder in Australia: findings from a population-based, cross-sectional study

2012; Springer Science+Business Media; Volume: 22; Issue: 1 Linguagem: Inglês

10.1007/s11136-012-0128-4

1573-2649

Adrienne O’Neil, Christopher Stevenson, Emily D. Williams, Duncan Mortimer, Brian Oldenburg, Kristy Sanderson,

Health disparities and outcomes

Health-related quality of life (HRQOL) can be significantly impaired by the presence of chronic conditions such as cardiovascular disease (CVD) and major depressive disorder (MDD). The aim of this paper was to (1) identify differences in HRQOL between individuals with CVD, MDD, or both, compared to a healthy reference group, (2) establish whether the influence of co-morbid MDD and CVD on HRQOL is additive or synergistic and (3) determine the way in which depression severity interacts with CVD to influence overall HRQOL.