Effects of Pycnogenol on endothelial function in patients with stable coronary artery disease: a double-blind, randomized, placebo-controlled, cross-over study
2012; Oxford University Press; Volume: 33; Issue: 13 Linguagem: Inglês
10.1093/eurheartj/ehr482
ISSN1522-9645
AutoresFrank Enseleit, Isabella Sudano, D Periat, Stephan Winnik, Mathias Wolfrum, Andreas J. Flammer, Georg Fröhlich, P. Kaiser, A. Hirt, Sarah R. Haile, Nazmi Krasniqi, Christian M. Matter, Klaus Uhlenhut, Petra Högger, Michel Neidhart, Thomas F. Lüscher, Frank Ruschitzka, G. Noll,
Tópico(s)Antioxidant Activity and Oxidative Stress
ResumoAimsExtracts from pine tree bark containing a variety of flavonoids have been used in traditional medicine. Pycnogenol is a proprietary bark extract of the French maritime pine tree (Pinus pinaster ssp. atlantica) that exerts antioxidative, anti-inflammatory, and anti-platelet effects. However, the effects of Pycnogenol on endothelial dysfunction, a precursor of atherosclerosis and cardiovascular events, remain still elusive.
Referência(s)