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Development of a Rubella Vaccination Strategy: Contribution of a Rubella Susceptibility Study of Women of Childbearing Age in Kyrgyzstan, 2001

2004; Oxford University Press; Volume: 38; Issue: 12 Linguagem: Inglês

10.1086/421018

1537-6591

Naile Malakmadze, Laura Zimmerman, Amra Uzicanin, Ludmila Shteinke, Victor M. Cáceres, Kaliya Kasymbekova, I. Sozina, John W. Glasser, M. Joldubaeva, Ch.K. Aidyralieva, Joseph P. Icenogle, Peter M. Strebel, Susan E. Reef,

Blood groups and transfusion

To contribute to the development of a rubella vaccination strategy, we conducted a study to determine age-specific susceptibility among women aged 15-39 years by testing for rubella-specific IgG antibodies. Of 964 women, 13% were found to be susceptible to rubella. Significantly higher susceptibility among women >25 years old was observed. Susceptibility data are important but are not sufficient to develop a vaccination strategy. After considering all available information, we suggested vaccination of women aged <35 years and selective vaccination of older women who were planning pregnancy.