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Relation between Microvolt-Level T-Wave Alternans and cardiac sympathetic nervous system abnormality using iodine-123 metaiodobenzylguanidine imaging in patients with Idiopathic Dilated cardiomyopathy

2003; Elsevier BV; Volume: 92; Issue: 8 Linguagem: Inglês

10.1016/s0002-9149(03)00988-3

1879-1913

Masahiko Harada, Akihiko Shimizu, Mariko Murata, Kaoru Ono, Makoto Kubo, Reo Mitani, Yuka Dairaku, Tomo Matsumoto, Toshihiko Yamagata, Kouzaburou Seki, Masunori Matsuzaki,

Cardiac Imaging and Diagnostics

We examined the relation between microvolt-level T-wave alternans and cardiac sympathetic nervous system abnormality using iodine-123 metaiodobenzylguanidine imaging in patients with idiopathic dilated cardiomyopathy. Our results strongly indicate that cardiac sympathetic denervation and accelerated sympathetic nervous activity play important roles in the presence of microvolt-level T-wave alternans in patients with idiopathic-dilated cardiomyopathy.