Contribution of Germline Mutations in the RAD51B , RAD51C , and RAD51D Genes to Ovarian Cancer in the Population
2015; Lippincott Williams & Wilkins; Volume: 33; Issue: 26 Linguagem: Inglês
10.1200/jco.2015.61.2408
ISSN1527-7755
AutoresHonglin Song, Ed Dicks, Susan J. Ramus, Jonathan P. Tyrer, Maria P. Intermaggio, Jane Hayward, Christopher K. Edlund, David V. Conti, Patricia Harrington, Lindsay Fraser, Susan Philpott, Christopher B. Anderson, Adam N. Rosenthal, Aleksandra Gentry‐Maharaj, David D.L. Bowtell, Kathryn Alsop, Mine S. Cicek, Julie M. Cunningham, Brooke L. Fridley, Jennifer Alsop, Mercedes Jimenez‐Liñan, Estrid Høgdall, Claus Høgdall, Allan Jensen, Susanne K. Kjær, Jan Lubiński, Tomasz Huzarski, Anna Jakubowska, Jacek Gronwald, Samantha Poblete, Shashi Lele, Lara E. Sucheston-Campbell, Kirsten B. Moysich, Kunle Odunsi, Ellen L. Goode, Usha Menon, Ian Jacobs, Simon A. Gayther, Paul D.P. Pharoah,
Tópico(s)Ovarian cancer diagnosis and treatment
ResumoThe aim of this study was to estimate the contribution of deleterious mutations in the RAD51B, RAD51C, and RAD51D genes to invasive epithelial ovarian cancer (EOC) in the population and in a screening trial of individuals at high risk of ovarian cancer.
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