Circadian Rhythms in 6-Sulphatoxymelatonin and Nocturnal Sleep in Blind Children
1991; Taylor & Francis; Volume: 8; Issue: 3 Linguagem: Inglês
10.3109/07420529109063923
ISSN1525-6073
AutoresOrna Tzischinsky, Debra J. Skene, Rachel Epstein, Peretz Lavie,
Tópico(s)Sleep and related disorders
ResumoThis article describes the relationship between melatonin secretion and sleep quality and subjective complaints about sleep in totally blind children. Eleven boarding-school children (mean age 15.2 years) participated. The major urinary melatonin metabolite 6-sulphatoxymelatonin (aMT6s) was measured five times a day for 48 h. Sleep-wake cycles were recorded by continuous actigraphic recordings during the same time period. Results showed that delayed secretory peaks in aMT6s were significantly associated with disturbed nocturnal sleep and with complaints about morning fatigue.
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