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Comparative uptake of free amino acids by mouse-ascites carcinoma cells and normal tissues.

1952; National Institutes of Health; Volume: 12; Issue: 3 Linguagem: Inglês

Halvor N. Christensen, Milton E. Henderson,

Biopolymer Synthesis and Applications

When mice bearing the Ehrlich ascites tumor were fed glycine or l-alanine, the carcinoma cells were more active in the accumulation of the free amino acid than the cells of liver or muscle. This superiority in amino acid accumulation is considered a significant factor in the growth and multiplication of the neoplastic cell in a wasting animal.