The Enigma of Intrahepatic Cholestasis of Pregnancy: Lessons from Chile
1982; Lippincott Williams & Wilkins; Volume: 2; Issue: 1 Linguagem: Inglês
10.1002/hep.1840020114
ISSN1527-3350
Autores Tópico(s)Pregnancy and Medication Impact
ResumoHepatologyVolume 2, Issue 1 p. 87S-96S ArticleFree Access The Enigma of Intrahepatic Cholestasis of Pregnancy: Lessons from Chile Humberto Reyes, Corresponding Author Humberto Reyes Departments of Medicine and Experimental Medicine, University of Chile School of Medicine, Hospital del Salvador, Santiago de ChileHumberto Reyes, M.D., Universidad de Chile, Departmento de Medicina Experimental Oriente, Casilla 16038, Santiago 9, Chile.===Search for more papers by this author Humberto Reyes, Corresponding Author Humberto Reyes Departments of Medicine and Experimental Medicine, University of Chile School of Medicine, Hospital del Salvador, Santiago de ChileHumberto Reyes, M.D., Universidad de Chile, Departmento de Medicina Experimental Oriente, Casilla 16038, Santiago 9, Chile.===Search for more papers by this author First published: January/February 1982 https://doi.org/10.1002/hep.1840020114Citations: 107AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References 1 Svanborg A. A study of recurrent jaundice in pregnancy. Acta Obstet Gynecol Scand 1954; 33: 434– 444. 2 Thorling L. Jaundice in pregnancy. A clinical study. Acta Med Scand 1955; 151: suppl 302. 3 Arfwedson H. General pruritus in pregnancy: symptom of liver dysfunction. Obstet Gynecol 1956; 7: 274– 276. 4 Kater RMH, Mistilis SP. Obstetric cholestasis and pruritus of pregnancy. Med J Aust 1967; 54: 638– 640. 5 Adlercreutz H, Svanborg A, Anberg A. Recurrent jaundice in pregnancy. II. A study of the estrogens and their conjugation in late pregnancy. Am J Med 1967; 42: 341– 347. 6 Eliakim M, Sadovsky E, Stein O, et al. Recurrent cholestatic jaundice of pregnancy. Report of five cases and electron microscopic observations. Arch Intern Med 1966; 117: 696– 705. 7 Haemmerli UP. Jaundice during pregnancy, with special emphasis on recurrent jaundice during pregnancy and its differential diagnosis. Acta Med Scand 1966; 179: suppl 4. 8 Ikonen E. Jaundice in late pregnancy. Acta Obstet Gynecol Scand 2 1966; 43: suppl 5. 9 Eppinger H. Die Leberkrankheiten. Vienna: Julius Springer, 1937. 10 Haemmerli UP, Wyss HI. Recurrent intrahepatic cholestasis of pregnancy. Report of six cases and review of the literature. Medicine (Bait) 1967; 46: 299– 321. 11 Sadovsky E, Eliakim M, Schenker JR. Pruritus gravidarum of hepatic origin. Isr J Med Sci 1970; 6: 540– 543. 12 Furhoff AK. Itching in pregnancy. A 15-year followup study. Acta Med Scand 1974; 196: 403– 410. 13 Samsioe G, Johnson P, Gustafson A. Aspects of the pathogenesis of cholestasis of pregnancy with reference to the serum lipid abnormalities. Scand J Gastroenterol 1975; 10: 1– 4. 14 Reyes H, Radrigán ME, Schramm G, et al. Frecuencia de la ictericia y prurito idiopático del embarazo en mujeres chilenas. Rev Med Chile 1968; 96: 409– 413. 15 Engström J, Hollström K, Posse N, et al. Recurrent cholestasis of pregnancy. Treatment with cholestyramine of one case with an unusually early onset. Acta Obstet Gynecol Scand 1970; 49: 29– 34. 16 Johnson P, Samsioe G, Gustafson A. Studies in cholestasis of pregnancy. I. Clinical aspects and liver function tests. Acta Obstet Gynecol Scand 1975; 54: 77– 84. 17 Svanborg A, Ohlsson S. Recurrent jaundice of pregnancy. A clinical study of twenty-two cases. Am J Med 1959; 27: 40– 49. 18 Adlercreutz H, Ikonen G. Oral contraceptives and liver damage. Br Med J 1964; 2: 1133. 19 Katz R, Velasco M, Reyes H. Ictericia por gestágenos. Su posible relatión con la ictericia idiopática del embarazo. Rev Med Chile 1966; 94: 3– 6. 20 Adlercreutz H, Tenhunen R. Some aspects of the interaction between natural and synthetic female sex hormones and the liver. Am J Med 1970; 49: 630– 648. 21 Combes B, Shibata H, Adams R, et al. Alterations in sulfobro-mophthalein sodium-removal mechanisms from blood during normal pregnancy. J Clin Invest 1963; 42: 1431– 1442. 22 Mueller MN, Kappas A. Estrogen pharmacology. I. Influence of estradiol and estriol on hepatic disposal of sulfobromophthalein (BSP) in man. J Clin Invest 1964; 43: 1905– 1914. 23 Kleiner GJ, Kresch L, Arias IM. Studies of hepatic excretory function. II. Effect of norethynodrel and mestranol on bromsulfal-ein sodium metabolism in women of childbearing age. N Engl J Med 1965; 273: 420– 423. 24 Bonorris GG, Coyne MJ, Chung A, et al. Mechanism of estrogen-induced saturated bile in the hamster. J Lab Clin Med 1977; 90: 963– 970. 25 Xern F Jr, Erfling W, Simon FR, et al. Effects of estrogens on the liver (clinical conference). Gastroenterology 1978; 75: 512– 522. 26 Reyes H, Kern F Jr. Effect of pregnancy on bile flow and biliary lipids in the hamster. Gastroenterology 1979; 76: 144– 150. 27 Kreek MJ, Weser E, Sleisenger MH, et al. Idiopathic cholestasis of pregnancy. The response to challenge with the synthetic estrogen, ethinyl estradiol. N Engl J Med 1967; 277: 1391– 1395. 28 Urban E, Frank BW, Kern F Jr, Liver dysfunction with mestranol but not with norethynodrel in a patient with Enovid-induced jaundice. Ann Intern Med 1968; 68: 598– 602. 29 Reyes H, Velasco M, Donoso S, et al. Estudio hepático seriado en mujeres que recibieron gestagenos. Rev Med Chile 1968; 96: 399– 404. 30 Reyes H, Aburto H, Ribalta J. Jaundice due to gestagens, revisited. Rev Med Chile 1978; 106: 85– 90. 31 Tikkanen MJ, Adlercreutz H. Recurrent jaundice in pregnancy. III. Quantitative determination of urinary estriol conjugates, including studies in pruritus gravidarum. Am J Med 1973; 54: 600– 604. 32 Adlercreutz H, Luukkainen T. Biochemical and clinical aspects of the enterohepatie circulation of estrogens. Acta Endocrinol (Kbh) 1967; 124: supp. 101. 33 Adlercreutz H, Tikkanen MJ, Wichmann K, et al. Recurrent jaundice in pregnancy. IV. Quantitative determination of urinary and biliary estrogens, including studies in pruritus gravidarum. J Clin Endocrinol Metab 1974; 38: 51– 57. 34 Eriksson H, Gustafsson JA, Sjövall J, et al. Excretion of neutral steroids in urine and faeces of women with intrahepatic cholestasis of pregnancy. Steroids Lipids Res 1972; 3: 30– 48. 35 Laatikainen T, Karjalainen O. Excretion of progesterone metabolites in urine and bile of pregnant women with intrahepatic cholestasis. J Steroid Biochem 1973; 4: 641– 648. 36 Sjövall J, Sjövall K. Steroid sulphates in plasma from pregnant women with pruritus and elevated plasma bile acid levels. Ann Clin Res 1970; 2: 321– 338. 37 Sjövall K, Sjövall J. Serum bile acid levels in pregnancy with pruritus (Bile acids and steroids 158). Clin Chim Acta 1966; 13: 207– 211. 38 Laatikainen T, Ikonen E. Serum bile acids in cholestasis of pregnancy. Obstet Gynecol 1977; 50: 313– 318. 39 Laatikainen T, Lehtonen P, Hesso A. Biliary bile acids in uncomplicated pregnancy and in cholestasis of pregnancy. Clin Chim Acta 1978; 85: 145– 150. 40 Samsioe G, Johnson P, Gustafson A. Studies in normal pregnancy. I. Serum lipids and fatty acid composition of serum phosphoglycerides. Acta Obstet Gynecol Scand 1975; 54: 265– 270. 41 Johnson P, Samsioe G, Gustafson A. Studies on cholestasis of pregnancy. II. Serum lipids and lipoproteins. Acta Obstet Gynecol Scand 1975; 54: 105– 111. 42 Johnson P. Studies in cholestasis of pregnancy. IV. Serum lipids and lipoprotein in relation to duration of symptoms and severity of the disease and fatty acid composition of lecithin in relation to duration of symptoms. Acta Obstet Gynecol Scand 1975; 54: 307– 313. 43 Johnson P, Olegard R, Samsioe G, et al. Studies in cholestasis of pregnancy. III Fatty acid composition of serum phosphoglycerides. Acta Obstet Gynecol Scand 1975; 54: 241– 246. 44 Samsioe G, Johnson P, Gustafson A. Studies in cholestasis of pregnancy. VI. Fatty acid composition of glycero-phospholipids before and after delivery. Acta Obstet Gynecol Scand 1977; 56: 31– 35. 45 Simcock MJ, Forster FMC. Pregnancy is cholestatic. Med J Aust 1967; 2: 971– 973. 46 Perreau P, Rouchy R. Ictere cholostatique recidivant de la gros-sesse. Gynecol Obstet (Paris) 1961; 60: 161– 179. 47 MacAllister JE, Waddell JM. Recurring idiopathic jaundice in pregnancy. Am J Obstet Gynecol 1962; 84: 62– 64. 48 Fast BB, Roulston TM. Idiopathic jaundice of pregnancy. Am J Obstet Gynecol 1964; 88: 314– 321. 49 Laatikainen TJ. Fetal bile acid levels in pregnancies complicated by maternal intrahepatic cholestasis. Am J Obstet Gynecol 1975; 122: 852– 856. 50 Mery A, Iturriaga S, Leal G, et al. Cinco años de experiencia en ictericias colestásicas del embarazo. XIII. Congreso Chileno de Obstetricia y Ginecologia. Imp. Siglo Veinte, Santiago, Nov. 1969, 422– 425. 51 Iglesias J, Galán G, Guerrero B, et al. Pruebas de madurez fetal, resolutión del parto y resultados del recién nacido en 91 casos de colestasia intrahepatica del embarazo. Rev Chil Obstet Ginecol 1976; 41: 278– 284. 52 Laatikainen TJ, Peltonen JI, Nylander PL. Effect of maternal intrahepatic cholestasis on fetal steroid metabolism. J Clin Invest 1974; 53: 1709– 1715. 53 Reyes H, González MC, Ribalta J, et al. Prevalence of intrahepatic cholestasis of pregnancy in Chile. Ann Intern Med 1978; 88: 487– 493. 54 Reyes H, Taboada G, Ribalta J. Prevalence of intrahepatic cholestasis of pregnancy in La Paz, Bolivia. J Chronic Dis 1979; 32: 499– 504. 55 Dalén E, Westerholm B. Occurrence of hepatic impairment in women jaundiced by oral contraceptives and in their mothers and sisters. Acta Med Scand 1974; 195: 459– 463. 56 Reyes H, Ribalta J, González-Cerón M. Idiopathic cholestasis of pregnancy in a large kindred. Gut 1976; 17: 709– 713. 57 Kreek MJ, Sleisenger MH, Jeffries GH. Recurrent cholestatic jaundice of pregnancy with demonstrated estrogen sensitivity. Am J Med 1967; 43: 795– 798. 58 Reyes H, Ribalta J, Gonzalez MC, et al. Sulfobromophthalein clearance tests before and after ethinyl estradiol administration, in women and men with familial history of intrahepatic cholestasis of pregnancy. Gastroenterology 1981; 81: 226– 331. 59 Cahill KM. Hepatitis in pregnancy. Surg Gynecol Obstet 1962; 114: 545– 552. 60 Roszkowski I, Wojcicka J. Jaundice in pregnancy. Am J Obstet Gynecol 1968; 102: 839– 846. 61 Creze B cited by Gagnaire JC, Descos L, Magnin P. Signification du prurit au cours de la grossesse. Relations avec les troubles hepatiques de la gestation. Nouv Presse Med 1975; 4: 1105– 1108. 62 Adlercreutz H, Martin F, Pulkkinen M, et al. Intestinal metabolism of estrogens. J Clin Endocrinol Metab 1976; 43: 497– 505. 63 Ylöstalo P. Liver function in hepatosis of pregnancy and preeclampsia, with special reference to modified bromsulphthalein tests. Acta Obstet Gynecol Scand 1970; 49: suppl 4. 64 Furhoff AK, Helström K. Jaundice in pregnancy. A follow-up study of the series of women originally reported by L. Thorling. I. The pregnancies. Acta Med Scand 1973; 193: 259– 266. 65 Furhoff AK, Hellström K. Jaundice in pregnancy. A follow-up study of the series of women originally reported by L. Thorling. II. Present health of the women. Acta Med Scand 1974; 196: 181– 189. 66 Johnson P, Samsioe G, Gustafson A. Studies in cholestasis of pregnancy. I. Clinical aspects and liver function tests. Acta Obstet Gynecol Scand 1975; 54: 77– 84. 67 Samsioe G, Svendsen P, Johnson P, et al. Studies in cholestasis of pregnancy. V. Gallbladder disease, liver function tests, serum lipids and fatty acid composition of serum lecithin in the non-pregnant state. Acta Obstet Gynecol Scand 1975; 54: 417– 423. 68 Braverman DZ, Johnson ML, Kern F Jr, Effects of pregnancy and contraceptive steroids on gallbladder function. N Engl J Med 1980; 302: 362– 364. 69 Ylöstalo P, Kirkinen P, Heikkinen J, et al. Gallbladder volume in cholestasis of pregnancy. N Engl J Med 1981; 304: 359. 70 Valdivieso V, Palma R, Nervi F, et al. Secretion of biliary lipids in young Chilean women with cholesterol gallstones. Gut 1979; 20: 997– 1000. 71 Nervi F. Covarrubias CF, Valdivieso VD, et al. Hepatic cholester-ogenesis in Chileans with cholesterol gallstone disease. Evidence for sex differences in the regulation of hepatic cholesterol metabolism. Gastroenterology 1981; 80: 539– 545. 72 De Pagter AGF, Van Berge Henegouwen GP, Ten Bokkel Huinink JA, et al. Familial benign recurrent intrahepatic cholestasis. Interrelation with intrahepatic cholestasis of pregnancy and from oral contraceptives? Gastroenterology 1976; 71: 202– 207. Citing Literature Volume2, Issue1January/February 1982Pages 87S-96S ReferencesRelatedInformation
Referência(s)