No evidence for aluminum in etiology and pathogenesis of alzheimer's disease
1986; Elsevier BV; Volume: 7; Issue: 6 Linguagem: Inglês
10.1016/0197-4580(86)90103-x
ISSN1558-1497
AutoresHenry M. Wisniewski, R. C. Moretz, Khalid Iqbal,
Tópico(s)Trace Elements in Health
ResumoThe review by Crapper McLachlan provides a one sided view in support of the possible role of aluminum in Alzheimer's disease without going into the biology, pathology and biochemistry of the disease or the disease process. Aluminum has been implicated as a cause or an important factor in Alzheimer's disease, amyotrophic lateral sclerosis (ALS), ALS-parkinsonism dementia and dialysis dementia. However, outside of the dialysis dementia syndrome, to date there is no evidence that aluminum has a role in the observed pathological changes, signs and symptoms in any of these diseases.
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