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A Mitogen-Activated Protein Kinase That Senses Nitrogen Regulates Conidial Germination and Growth in Aspergillus fumigatus

2004; American Society for Microbiology; Volume: 3; Issue: 2 Linguagem: Inglês

10.1128/ec.3.2.557-560.2004

1535-9778

Tao Xue, C. Kim Nguyen, Angela Romans, Gregory S. May,

Antifungal resistance and susceptibility

ABSTRACT We show that the mitogen-activated protein (MAP) kinase pathway that responds to osmotic stress in Aspergillus fumigatus is also involved in nutritional sensing. This MAP kinase regulates conidial germination in response to the nitrogen source and is activated upon starvation for either carbon or nitrogen during vegetative growth.