Artigo Acesso aberto Produção Nacional Revisado por pares

Perfil das doenças glomerulares em um hospital público do Distrito Federal

2010; Sociedade Brasileira de Nefrologia; Volume: 32; Issue: 3 Linguagem: Inglês

10.1590/s0101-28002010000300005

ISSN

2175-8239

Autores

Fábio Humberto Ribeiro Paes Ferraz, Carla Guapindaia Braga Martins, Janaína Costa Cavalcanti, Frederico Lopes de Oliveira, Renata Miguel Quirino, Rosana Chicon, Sergio Raimundini Cavechia,

Tópico(s)

Chronic Kidney Disease and Diabetes

Resumo

Glomerular diseases are a frequent etiology of chronic kidney disease, especially in the developing countries.To determine the profile of such glomerulopathies in a public hospital located in the city of Brasilia, Federal District.121 renal biopsies in different patients were performed by the Renal Division of Hospital Regional da Asa Norte (HRAN) between August 2005 and May 2009. Eight renal biopsies in renal-transplant patients were excluded and the medical records of 113 remaining patients were analyzed. Analyzed data: sex, age, laboratory exams, glomerular syndrome, clinical diagnosis, degree of interstitial fibrosis, immunosuppressants use, need for dialysis and clinical outcome.The age average was 34.9 ± 16.2 years-old, a predominance of male patients (51.3%). Major glomerular syndromes were: nephrotic syndrome (41.6%) and the rapidly- progressive glomerulonephritis (35.4%). Among primary glomerulopathies focal glomerulosclerosis (26.8%) followed by IgA nephropathy (25%) were predominant; and among the most prevalent secondary glomerulopathies we had lupus nephritis (50%) and diffuse exudative proliferative glomerulonephritis (34.2%).The majority of the patients used immunosuppressants (68.1%) and almost one third of them (29.2%) needed dialysis during their hospitalization. Progressed to chronic dialysis therapy 13.3% of the patients and 10.6% died.This study may contribute to better epidemiological understanding of glomerular diseases in the Federal District, guiding the adoption of public policies aiming the quick clinical treatment of such diseases.

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