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BIBTEX RIS

Analysis of genetic systems using experimental evolution and whole-genome sequencing

2007; BioMed Central; Volume: 8; Issue: 1 Linguagem: Inglês

10.1186/gb-2007-8-1-201

ISSN

1474-760X

Autores

Matthew Hegreness, Roy Kishony,

Tópico(s)

Bioinformatics and Genomic Networks

Resumo

The application of whole-genome sequencing to the study of microbial evolution promises to reveal the complex functional networks of mutations that underlie adaptation. A recent study of parallel evolution in populations of Escherichia coli shows how adaptation involves both functional changes to specific proteins as well as global changes in regulation.

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