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Cromoblastomicose produzida por Fonsecaea pedrosoi no Estado do Maranhão. I - aspectos clínicos, epidemiológicos e evolutivos

1992; Brazilian Society of Tropical Medicine; Volume: 25; Issue: 1 Linguagem: Inglês

10.1590/s0037-86821992000100006

1678-9849

Ana Carla C. Mello e Silva, Artur Serra Neto, Cloves Eduardo S. Galvão, Sirley Garcia Marques, Ana Cristina R. Saldanha, Conceição de Maria Pedroso e Silva, Olga Fischman, Raimunda Ribeiro da Silva, Maria do Rosário da S. R. Costa, Jackson Maurício Lopes Costa,

Antifungal resistance and susceptibility

The aim of this study was to observe the clinical and of epidemiological behavior of chromoblastomycosis in the State of Maranhão. A retrospective and prospective study of 13 cases was performed at the infectious diseases section of the Hospital dos Servidores do Estado do Maranhão, from November, 1988 to July, 1991. In the investigation a protocol record was used with a view to further analysis. A higher prevalence between 50 and 60 years of age (46.1%) and in male patients (92.3%) was noted. Twelve patients (92.3%) were from Maranhão State, and 10 of them (76.9%) came from the western microregion of the State of Maranhão. Regarding occupation, 92.3% were land workers, and most of them presented the lesions on the lower limbs (84.6%) of a vegetant warty aspect, brown in color with itching. Histopathological examination diagnosed chromomycosis in 100% of the cases. Culture was performed in 11 cases, and Fonsecaea pedrosoi isolated in 9 of them. Treatment with 5-fluorocytosine resulted in a good evolutive response. This study indicates the existence of a probable endemic area of chromomycosis in hinterland of Maranhão (western microregion) that hither to unknown.