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Topical treatments for hypertrophic scars

2006; Elsevier BV; Volume: 55; Issue: 6 Linguagem: Inglês

10.1016/j.jaad.2006.03.022

1097-6787

Joanna M. Zurada, David Kriegel, Ira C. Davis,

Wound Healing and Treatments

Hypertrophic scars represent an abnormal, exaggerated healing response after skin injury. In addition to cosmetic concern, scars may cause pain, pruritus, contractures, and other functional impairments. Therapeutic modalities include topical medications, intralesional corticosteroids, laser therapy, and cryosurgery. Topical therapies, in particular, have become increasingly popular because of their ease of use, comfort, noninvasiveness, and relatively low cost. This review will discuss the properties and effectiveness of these agents, including pressure therapy, silicone gel sheeting and ointment, polyurethane dressing, onion extract, imiquimod 5% cream, and vitamins A and E in the prevention and treatment of hypertrophic scars.