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Statin use and cancer risk in the General Practice Research Database

2004; Springer Nature; Volume: 90; Issue: 3 Linguagem: Inglês

10.1038/sj.bjc.6601566

1532-1827

James A. Kaye, Hershel Jick,

Genetic factors in colorectal cancer

In a matched case–control study using the General Practice Research Database, current statin use was not associated with a significantly altered risk of any of 13 studied cancers. Untreated hyperlipidaemia was associated with slightly increased risks of colon cancer (relative risk 1.8; 95% confidence interval 1.2–2.8), prostate cancer (1.5; 1.1–2.0), and bladder cancer (1.9; 1.2–3.1).