Portal de Periódicos da CAPES

Kinetics of Conformational Sampling in Ubiquitin

2011; Wiley; Volume: 50; Issue: 48 Linguagem: Inglês

10.1002/anie.201105086

1521-3773

David Ban, Michael A. Funk, R. Gulich, Dalia Egger, T. Michael Sabo, Korvin F. A. Walter, R. Bryn Fenwick, Karin Giller, Fabio Pichierri, Bert L. de Groot, Oliver F. Lange, Helmut Grubmüller, Xavier Salvatella, Martin Wolf, A. Loidl, Reiner Kree, Stefan Becker, Nils‐Alexander Lakomek, Donghan Lee, P. Lunkenheimer, Christian Griesinger,

Advanced MRI Techniques and Applications

A good combination: The lifetime of interconversion among the ground states of a protein ensemble representation could only be assigned to a time window that is four orders of magnitude large and ranges from 4 ns to 50 μs. By combining temperature-dependent NMR relaxation dispersion (RD) experiments and dielectric relaxation (DR) spectroscopy in solution, the lifetime was now identified to a value of (10±9) μs at 309 K. Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.