Portal de Periódicos da CAPES

Multiple sclerosis–associated retrovirus (MSRV) in Sardinian MS patients

2002; Lippincott Williams & Wilkins; Volume: 58; Issue: 3 Linguagem: Inglês

10.1212/wnl.58.3.471

1526-632X

Antonina Dolei, Caterina Serra, Giuseppe Mameli, Maura Pugliatti, GianPietro Sechi, M. C. Cirotto, Giulio Rosati, Stefano Sotgiu,

Herpesvirus Infections and Treatments

Blood and CSF of Sardinian patients with MS and neurologic control subjects were tested for MS-associated retrovirus (MSRV). CSF detection in MS was 50% at clinical onset, increasing with temporal disease progression, and 40% in control subjects. In blood, MSRV was detected in all MS patients, in most patients with inflammatory neurologic diseases, and rarely in healthy blood donors. MSRV may represent a marker of neurologic diseases of inflammatory origin.