Artigo Acesso aberto Produção Nacional Revisado por pares

Adiposity markers and risk of coronary heart disease in patients with type 2 diabetes mellitus

2014; BioMed Central; Volume: 13; Issue: 1 Linguagem: Inglês

10.1186/1475-2891-13-124

ISSN

1475-2891

Autores

Simone Frederico Tonding, Flávia Moraes Silva, Juliana Peçanha Antonio, Mirela Jobim de Azevedo, Luís Henrique Santos Canani, Jussara Carnevale de Almeida,

Tópico(s)

Obesity, Physical Activity, Diet

Resumo

This cross-sectional study aimed to evaluating the association between body adiposity markers and high-risk of coronary heart disease (CHD) in patients with type 2 diabetes. Recent adiposity markers [waist-to-height ratio, conicity index (C-index) and body adiposity index] and traditional markers [BMI, waist circumference and waist-to-hip ratio (WHR)] were measured. The 10-year risk of fatal CHD was estimated according to UKPDS risk engine scores. Patients were divided into high (CHD risk ≥20%; n = 99) or low-moderate (CHD risk 20% (OR = 1.69; 95% CI 1.03-2.78; P = 0.039) after adjusting for confounders (sedentary lifestyle, diabetic nephropathy, serum creatinine, and diabetes duration). The association between WHR and CHD risk did not hold in this sample. The C-index was the body adiposity marker best associated with high risk of fatal CHD in these patients with type 2 diabetes.

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