Allergenic potential of Arnica -containing formulations in Arnica -allergic patients
2009; Wiley; Volume: 61; Issue: 5 Linguagem: Inglês
10.1111/j.1600-0536.2009.01638.x
ISSN1600-0536
AutoresAndrea Jocher, G. Nist, Johannes M. Weiss, Dieter Wetzel, Irmgard Merfort, Thilo Jakob, Christoph M. Schempp,
Tópico(s)Plant Toxicity and Pharmacological Properties
ResumoContact DermatitisVolume 61, Issue 5 p. 304-306 Allergenic potential of Arnica-containing formulations in Arnica-allergic patients Andrea Jocher, Andrea Jocher Department of Dermatology and Allergology, University Medical Center Freiburg, FreiburgSearch for more papers by this authorGabriele Nist, Gabriele Nist Department of Dermatology and Allergology, Hospital Bad Cannstatt, Bad, CannstattSearch for more papers by this authorJohannes M. Weiss, Johannes M. Weiss Department of Dermatology and Allergology, University of Ulm, UlmSearch for more papers by this authorDieter Wetzel, Dieter Wetzel Toclinco Contract Research Organization, FreiburgSearch for more papers by this authorIrmgard Merfort, Irmgard Merfort Department of Pharmaceutical Biology and Biotechnology, University of Freiburg, Freiburg, GermanySearch for more papers by this authorThilo Jakob, Thilo Jakob Department of Dermatology and Allergology, University Medical Center Freiburg, FreiburgSearch for more papers by this authorChristoph M. Schempp, Corresponding Author Christoph M. Schempp Department of Dermatology and Allergology, University Medical Center Freiburg, FreiburgChristoph M. Schempp, MDDepartment of DermatologyUniversity Medical Center FreiburgHauptstrasse 7D-79104 Freiburg, GermanyTel: ++49 761 270 6701Fax: ++49 761 270 6829e-mail:[email protected]Search for more papers by this author Andrea Jocher, Andrea Jocher Department of Dermatology and Allergology, University Medical Center Freiburg, FreiburgSearch for more papers by this authorGabriele Nist, Gabriele Nist Department of Dermatology and Allergology, Hospital Bad Cannstatt, Bad, CannstattSearch for more papers by this authorJohannes M. Weiss, Johannes M. Weiss Department of Dermatology and Allergology, University of Ulm, UlmSearch for more papers by this authorDieter Wetzel, Dieter Wetzel Toclinco Contract Research Organization, FreiburgSearch for more papers by this authorIrmgard Merfort, Irmgard Merfort Department of Pharmaceutical Biology and Biotechnology, University of Freiburg, Freiburg, GermanySearch for more papers by this authorThilo Jakob, Thilo Jakob Department of Dermatology and Allergology, University Medical Center Freiburg, FreiburgSearch for more papers by this authorChristoph M. Schempp, Corresponding Author Christoph M. Schempp Department of Dermatology and Allergology, University Medical Center Freiburg, FreiburgChristoph M. Schempp, MDDepartment of DermatologyUniversity Medical Center FreiburgHauptstrasse 7D-79104 Freiburg, GermanyTel: ++49 761 270 6701Fax: ++49 761 270 6829e-mail:[email protected]Search for more papers by this author First published: 28 October 2009 https://doi.org/10.1111/j.1600-0536.2009.01638.xCitations: 4 Conflict of interest: This work was commissioned and funded by Kneipp Werke, Wüzburg, Germany. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Lyss G, Knorre A, Schmidt T J, Pahl H L, Merfort I. The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-kappaB by directly targeting p65. J Biol Chem 1998: 273: 33508– 33516. 2 Lass C, Vocanson M, Wagner S, Schempp C M, Nicolas J F, Merfort I, Martin SF. Anti-inflammatory and immune-regulatory mechanisms prevent contact hypersensitivity to Arnica montana L. Exp Dermatol 2008: 17: 849– 857. 3 Wagner S, Merfort I. Skin penetration behaviour of sesquiterpene lactones from different Arnica preparations using a validated GC-MSD method. J Pharm Biomed Anal 2007: 1: 32– 38. 4 Tekko I A, Bonner M C, Bowen R D, Williams A C. Permeation of bioactive constituents from Arnica montana preparations through human skin in vitro. J Pharm Pharmacol 2006: 58: 1167– 1176. 5 Wagner S, Suter A, Merfort I. Skin penetration studies of Arnica preparations and of their sesquiterpene lactones. Planta Med 2004: 70: 897– 903. 6 Ekenäs C, Zebrowska A, Schuler B, Vrede T, Andreasen K, Backlund A, Merfort I, Bohlin L. Screening for anti-inflammatory activity of 12 Arnica (Asteraceae) species assessed by inhibition of NF-kappaB and release of human neutrophil elastase. Planta Med 2008: 74: 1789– 1794. 7 Passreiter C M, Florack M, Willuhn G, Goerz G. Allergic contact dermatitis caused by Asteraceae. Identification of an 8,9-epoxythymol-diester as the contact allergen of Arnica sachalinensis. Derm Beruf Umwelt 1988: 36: 79– 82. 8 Lepoittevin J P, Tomb R. Sesquiterpene lactone mix is not an adequate screen for Compositae allergy. Contact Dermatitis 1995: 4: 254. 9 Green C, Ferguson J. Sesquiterpene lactone mix is not an adequate screen for Compositae allergy. Contact Dermatitis 1994: 3: 151– 153. 10 Von der Werth J M, Ratcliffe J, English J S. Compositae mix is a more sensitive test for Compositae dermatitis than the sesquiterpene lactone mix. Contact Dermatitis 1999: 5: 273– 276. 11 Paulsen E, Christensen L P, Andersen K E. Cosmetics and herbal remedies with Compositae plant extracts– are they tolerated by Compositae-allergic patients? Contact Dermatitis 2008: 58: 15– 23. 12 Hausen B M. Arnica allergy. Hautarzt 1980: 31: 10– 17. Citing Literature Volume61, Issue5November 2009Pages 304-306 ReferencesRelatedInformation
Referência(s)