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Health-related quality of life in small-cell lung cancer: a systematic review on reporting of methods and clinical issues in randomised controlled trials

2014; Elsevier BV; Volume: 15; Issue: 2 Linguagem: Inglês

10.1016/s1470-2045(13)70493-5

1474-5488

Efstathios Zikos, Irina Ghislain, Corneel Coens, Divine Ediebah, Elizabeth K. Sloan, Chantal Quinten, Michael Koller, Jan P. van Meerbeeck, Hans‐Henning Flechtner, Roger Stupp, Athanasios Pallis, Agnes Czimbalmos, Mirjam A. G. Sprangers, Andrew Bottomley,

Lung Cancer Treatments and Mutations

Small-cell lung cancer represents about 15% of all lung cancers; increasingly, randomised controlled trials of this disease measure the health-related quality of life of patients. In this Systematic Review we assess the adequacy of reporting of health-related quality-of-life methods in randomised controlled trials of small-cell lung cancer, and the potential effect of this reporting on clinical decision making. Although overall reporting of health-related quality of life was acceptable, improvements are needed to optimise the use of health-related quality of life in randomised controlled trials.