Lymphocytic Interstitial Pneumonia: Thin-Section CT Findings in 22 Patients
1999; Radiological Society of North America; Volume: 212; Issue: 2 Linguagem: Inglês
10.1148/radiology.212.2.r99au05567
ISSN1527-1315
AutoresTakeshi Johkoh, Néstor L. Müller, Heather A. Pickford, Thomas E. Hartman, Kazuya Ichikado, Masanori Akira, Osamu Honda, Hironobu Nakamura,
Tópico(s)IgG4-Related and Inflammatory Diseases
ResumoTo assess the thin-section computed tomographic (CT) findings of lymphocytic interstitial pneumonia.The study included 22 patients (five men, 17 women; age range, 24-83 years; mean age, 50 years) with biopsy-proved lymphocytic interstitial pneumonia. The CT scans were obtained by using 1-3-mm collimation and reconstructed by using a high-spatial-frequency algorithm.The predominant abnormalities consisted of areas of ground-glass attenuation and poorly defined centrilobular nodules present in all 22 patients and subpleural small nodules seen in 19 patients. Other common findings included thickening of bronchovascular bundles (n - 19), interlobular septal thickening (n = 18), cystic airspaces (n = 15), and lymph node enlargement (n = 15). Less common findings included large nodules, emphysema, airspace consolidation, bronchiectasis, architectural distortion, honeycombing, and pleural thickening.Lymphocytic interstitial pneumonia is characterized by the presence of ground-glass attenuation, poorly defined centrilobular nodules, and thickening of the interstitium along the lymphatic vessels. Lymph node enlargement is more common than previously recognized; it was seen in 68% of patients.
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