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Mielinólise pontina central e extra-pontina em paciente alcoolista sem distúrbios hidro-eletrolíticos: relato de caso

2002; Thieme Medical Publishers (Germany); Volume: 60; Issue: 4 Linguagem: Inglês

10.1590/s0004-282x2002000600028

1678-4227

Francisco Manoel Branco Germiniani, Maurício M. Roriz, Samir Kanaan Nabhan, Hélio Afonso Ghizoni Teive, Lineu César Werneck,

Pharmacological Effects and Toxicity Studies

Central pontine myelinolysis (CPM) and extra-pontine myelinolysis (EPM) are different presentations of a demyelinating disorder of the brain more commonly associated with rapid correction of hyponatremia, spastic tetraparesia and pseudo-bulbar palsy. There are in the literature a few cases of CPM/EPM in patients without electrolyte disturbances. We report the case of a 39 year-old man with severe alcoholism, who presented with spastic tetraparesis and palsy of several cranial nerves, associated with lesions in the magnetic resonance compatible with CPM/EPM. The patient had a good follow-up after pulse therapy with corticosteroids.