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Synthesis and biological evaluation of potential small moleculeinhibitors of tumor necrosis factor

2015; Royal Society of Chemistry; Volume: 6; Issue: 6 Linguagem: Inglês

10.1039/c5md00023h

2040-2511

Christos Papaneophytou, Polyxeni Alexiou, Athanasios Papakyriakou, Evangelos Ntougkos, Katerina Tsiliouka, Anna Maranti, Fotini Liepouri, A. T. Strongilos, Anthi Mettou, Elias A. Couladouros, Elias Eliopoulos, Eleni Douni, George Kollias, George Kontopidis,

Cytokine Signaling Pathways and Interactions

A series of 39 novel SPD-304 analogs were designed synthesized and evaluated as inhibitors of TNF.