Understanding of nanogels swelling behavior through a deep insight into their morphology
2015; Wiley; Volume: 53; Issue: 17 Linguagem: Inglês
10.1002/pola.27653
ISSN1099-0518
AutoresAintzane Pikabea, G. Aguirre, José I. Miranda, José Ramos, Jacqueline Forcada,
Tópico(s)Advanced Polymer Synthesis and Characterization
ResumoABSTRACT A thorough understanding of the morphology of the environmental sensitive nanogels was indispensable to obtain a deeper insight on their stimuli‐responsive behavior. Therefore, in this work the colloidal characterization and the study of the inner morphology were related by using light scattering technique and 1 H‐nuclear magnetic resonance transverse relaxation measurements combined with the Flory–Rehner theory. Different biocompatible and dual‐stimuli‐sensitive nanogel particles based on poly(2‐diethylaminoethyl) methacrylate were synthesized using three different crosslinkers: two bifunctional and one multifunctional. All the nanogels obtained had a core–shell type heterogeneous morphology, but they presented completely different swelling behaviors due to their different crosslinking points’ distribution and polymeric chains’ microstructure. © 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2015 , 53 , 2017–2025
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