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BIBTEX RIS

SNPmasker: automatic masking of SNPs and repeats across eukaryotic genomes

2006; Oxford University Press; Volume: 34; Issue: Web Server Linguagem: Inglês

10.1093/nar/gkl125

ISSN

1362-4962

Autores

Reidar Andreson, Tarmo Puurand, Maido Remm,

Tópico(s)

Chromosomal and Genetic Variations

Resumo

SNPmasker is a comprehensive web interface for masking large eukaryotic genomes.The program is designed to mask SNPs from recent dbSNP database and to mask the repeats with two alternative programs.In addition to the SNP masking, we also offer population-specific substitution of SNP alleles in genomic sequence according to SNP frequencies in HapMap Phase II data.The input to SNPmasker can be defined in chromosomal coordinates or inserted as a sequence.The sequences masked by our web server are most useful as a preliminary step for different primer and probe design tasks.The service is available at http://bioinfo.ebc.ee/snpmasker/ and is free for all users.

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