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Effect of Y chromosome and H-2 complex derived from Japanese wild mouse on sperm morphology

1989; Cambridge University Press; Volume: 53; Issue: 1 Linguagem: Inglês

10.1017/s0016672300027816

1469-5073

Dong-Sang Suh, Józefa Styrna, Kazuo Moriwaki,

Animal Genetics and Reproduction

Summary Segregation of sperm abnormality level and H-2 haplotypes was investigated in F2 hybrid males obtained from reciprocal crosses involving two B10.congenic strains carrying H-2 and the Y chromosome of Japanese wild mice: B10.MOL-OHM ( H-2 ωm4 , 23·1% of sperm abnormalities) and B10.MOL-OKB ( H-2 ωm8 , 11·1% of sperm abnormalities). In both types of crosses mean levels of abnormal spermatozoa were significantly higher for males typed as H-2 ωm4 / H-2 ωm4 than for heterozygous H-2 ωm4 / H-2 ωm8 or homozygous H-2 ωm8 / H-2 ωm8 . These results suggest that the gene for high sperm abnormality is linked to H-2 complex of the B10.MOL-OHM strain.