Produção Nacional
Revisado por pares
PROXIMAL INSERTION OF GUBERNACULUM TESTIS IN NORMAL HUMAN FETUSES AND IN BOYS WITH CRYPTORCHIDISM
2000; Lippincott Williams & Wilkins; Volume: 164; Issue: 3 Part 1 Linguagem: Inglês
10.1016/s0022-5347(05)67315-6
ISSN1527-3792
AutoresLuciano A. Favorito, Francisco J.B. Sampaio, Valter Javaroni, Luiz E.M. Cardoso, Waldemar S. Costa,
Tópico(s)Urologic and reproductive health conditions
ResumoNo AccessJournal of UrologyPEDIATRIC UROLOGY1 Sep 2000PROXIMAL INSERTION OF GUBERNACULUM TESTIS IN NORMAL HUMAN FETUSES AND IN BOYS WITH CRYPTORCHIDISM LUCIANO A. FAVORITO, FRANCISCO J.B. SAMPAIO, VALTER JAVARONI, LUIZ E. MACEDO CARDOSO, and WALDEMAR S. COSTA LUCIANO A. FAVORITOLUCIANO A. FAVORITO More articles by this author , FRANCISCO J.B. SAMPAIOFRANCISCO J.B. SAMPAIO More articles by this author , VALTER JAVARONIVALTER JAVARONI More articles by this author , LUIZ E. MACEDO CARDOSOLUIZ E. MACEDO CARDOSO More articles by this author , and WALDEMAR S. COSTAWALDEMAR S. COSTA More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)67315-6AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We determine how the proximal gubernaculum testis is attached to the testis and epididymis in human fetuses, and compare these data with findings in boys who had undergone surgery for cryptorchidism. Materials and Methods: We analyzed 280 testes and epididymides with the gubernacula of 140 well preserved, fresh human fetuses ranging from 10 to 35 weeks after conception with no detectable congenital malformations and 36 undescended testes of 28 boys 2 to 15 years old (mean age 6.8) who had undergone surgery for cryptorchidism. In both groups the different conformations of the relationship among the proximal gubernaculum, testis and epididymis were classified according to a system used for patients with cryptorchidism. In group A the gubernaculum is attached to the testis and epididymis, in group B the gubernaculum is attached only to the testis with a tail disjunction epididymal anomaly, in group C the gubernaculum is attached only to the testis with total disjunction of the epididymis, in group D the gubernaculum is attached only to the epididymal tail and in group E there are no attachments among gubernaculum, testis and epididymis. Results: Of the 280 fetal testes studied 194 (69.2%) were in the abdomen, 38 (13.57%) in the inguinal canal and 48 (17.14%) in the scrotum. There were 277 cases (98.9%) in group A and 3 (1.1%) in group B. Of the 36 undescended testes analyzed 2 (5.6%) were abdominal and 34 (94.4%) were inguinal. There were 26 cases (72.2%) in group A, 8 (22.2%) in group B and 2 in group D. Conclusions: In fetuses without congenital malformations or epididymal alterations, such as tail disjunction or elongated epididymis, the proximal portion of the gubernaculum was attached to the testis and epididymis in all cases. In undescended testes there was an increased incidence of paratesticular structure malformations accompanied by gubernacular attachment anomalies compared to the testes in normal fetuses. References 1 : Embryology of testicular descent and maldescent. Urol Clin North Am1982; 9: 315. Google Scholar 2 : Mechanism of testicular descent. Urol Res1984; 12: 155. Google Scholar 3 : Androgenic sensitivity of the gubernaculum testis: evidence for hormonal/mechanical interactions in testicular descent. J Urol1982; 127: 170. Link, Google Scholar 4 : Hormonal regulation of testicular descent: experimental and clinical observations. J Urol1977; 118: 985. Google Scholar 5 : Historical review of theories on testicular descent. J Urol1995; 153: 754. 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Google Scholar From the Urogenital Research Unit, State University of Rio de Janeiro, Rio de Janeiro, Brazil© 2000 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byCosta S, Costa W, Sampaio F and Favorito L (2014) Structural Study of Gubernaculum Testis in Fetuses with Prune Belly SyndromeJournal of Urology, VOL. 193, NO. 5S, (1830-1836), Online publication date: 1-May-2015.FAVORITO L, KLOJDA C, COSTA W and SAMPAIO F (2018) Is there a Relationship with Anomalous Insertions of the Distal Gubernaculum Testis and Testicular Ectopia? Analysis in Human Fetuses and Patients with CryptorchidismJournal of Urology, VOL. 170, NO. 2, (554-557), Online publication date: 1-Aug-2003.COSTA W, SAMPAIO F, FAVORITO L and CARDOSO L (2018) Testicular Migration: Remodeling of Connective Tissue and Muscle Cells in Human Gubernaculum TestisJournal of Urology, VOL. 167, NO. 5, (2171-2176), Online publication date: 1-May-2002. Volume 164Issue 3 Part 1September 2000Page: 792-794 Advertisement Copyright & Permissions© 2000 by American Urological Association, Inc.KeywordstestisepididymiscryptorchidismfetusMetricsAuthor Information LUCIANO A. FAVORITO More articles by this author FRANCISCO J.B. SAMPAIO More articles by this author VALTER JAVARONI More articles by this author LUIZ E. MACEDO CARDOSO More articles by this author WALDEMAR S. COSTA More articles by this author Expand All Advertisement PDF downloadLoading ...
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