Unexplained Macrocytosis in Elderly Patients
1996; Oxford University Press; Volume: 25; Issue: 4 Linguagem: Inglês
10.1093/ageing/25.4.310
ISSN1468-2834
AutoresMohamed Y. Mahmoud, Myriam Lugon, Christine Anderson,
Tópico(s)Bone and Joint Diseases
ResumoOne hundred and twenty-four patients over the age of 75 years were assessed for the cause of their macrocytosis (MCV > 95 fl). A definitive diagnosis was reached in 75/124 (60%) by non-invasive techniques. The remainder underwent a bone marrow biopsy yielding a definitive diagnosis in a further six patients who had an identifiable myelodysplastic syndrome (MDS). A high proportion of the remainder had morphological abnormalities which fitted with no recognized pathological entity. It is suggested that these may represent MDS in evolution.
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