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Confirmation of Putative HIV-1 Group P in Cameroon

2010; American Society for Microbiology; Volume: 85; Issue: 3 Linguagem: Inglês

10.1128/jvi.02005-10

1098-5514

Ana Vallari, Vera Holzmayer, Barbara J. Harris, Julie Yamaguchi, Charlotte Ngansop, Florence Makamche, Dora Mbanya, Lazare Kaptué, Nicaise Ndembi, Lutz Gürtler, Sushil G. Devare, Catherine A. Brennan,

Reproductive tract infections research

ABSTRACT We report the second human immunodeficiency virus (HIV) belonging to the new HIV type 1 (HIV-1) group P lineage that is closely related to the simian immunodeficiency virus found in gorillas. This virus was identified in an HIV-seropositive male hospital patient in Cameroon, confirming that the group P virus is circulating in humans. Results from screening 1,736 HIV-seropositive specimens collected in Cameroon indicate that HIV-1 group P infections are rare, accounting for only 0.06% of HIV infections. Despite its rarity, group P shows evidence of adaptation to humans.