Carotid body chemoreceptors: from natural stimuli to sensory discharges.
1994; American Physiological Society; Volume: 74; Issue: 4 Linguagem: Inglês
10.1152/physrev.1994.74.4.829
ISSN1522-1210
AutoresC. González, L. Almaraz, Ana Obeso, R. Rigual,
Tópico(s)Cardiovascular and Diving-Related Complications
ResumoCarotid body chemoreceptors: from natural stimuli to sensory discharges.C Gonzalez, L Almaraz, A Obeso, and R RigualC GonzalezDepartamento de Bioquímica y Biología Molecular y Fisiología, Facultad de Medicina, Universidad de Valladolid, Spain., L AlmarazDepartamento de Bioquímica y Biología Molecular y Fisiología, Facultad de Medicina, Universidad de Valladolid, Spain., A ObesoDepartamento de Bioquímica y Biología Molecular y Fisiología, Facultad de Medicina, Universidad de Valladolid, Spain., and R RigualDepartamento de Bioquímica y Biología Molecular y Fisiología, Facultad de Medicina, Universidad de Valladolid, Spain.Published Online:01 Oct 1994https://doi.org/10.1152/physrev.1994.74.4.829MoreSectionsPDF (21 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformationCited ByCarotid Body Inflammation: Role in Hypoxia and in the Anti-inflammatory ReflexRodrigo Iturriaga, Rodrigo Del Rio, and Julio Alcayaga29 March 2022 | Physiology, Vol. 37, No. 3Effects of passive and active leg movements to interrupt sitting in mild hypercapnia on cardiovascular function in healthy adultsSong-Young Park,* TeSean K. 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Sterni1 May 2005 | American Journal of Physiology-Lung Cellular and Molecular Physiology, Vol. 288, No. 5CO2/pH Chemosensory Signaling in Co-Cultures of Rat Carotid Body Receptors and Petrosal Neurons: Role of ATP and AChMin Zhang, and Colin A. Nurse1 December 2004 | Journal of Neurophysiology, Vol. 92, No. 6Neurotransmission in the carotid body: transmitters and modulators between glomus cells and petrosal ganglion nerve terminalsBrain Research Reviews, Vol. 47, No. 1-3CO2 transduction mechanisms in avian intrapulmonary chemoreceptors: experiments and modelsRespiratory Physiology & Neurobiology, Vol. 144, No. 2-3Breathing pattern and hypoxic sensitivity during ageing in a new model of obesity-resistant ratRespiratory Physiology & Neurobiology, Vol. 144, No. 1Neuroepithelial oxygen chemoreceptors of the zebrafish gill29 October 2004 | The Journal of Physiology, Vol. 560, No. 3Detection of hypoxia-evoked ATP release from chemoreceptor cells of the rat carotid bodyBiochemical and Biophysical Research Communications, Vol. 322, No. 1Ion channel regulation by chronic hypoxia in models of acute oxygen sensingCell Calcium, Vol. 36, No. 3-4The role of calcium in hypoxia-induced signal transduction and gene expressionCell Calcium, Vol. 36, No. 3-4The impact of adenosine on the release of acetylcholine, dopamine, and norepinephrine from the cat carotid bodyNeuroscience Letters, Vol. 367, No. 3Genomic imprinting and environment in hereditary paraganglioma1 January 2004 | American Journal of Medical Genetics, Vol. 129C, No. 1Maturation of peripheral arterial chemoreceptors in relation to neonatal apnoeaSeminars in Neonatology, Vol. 9, No. 3Indirect sensing of insulin-induced hypoglycaemia by the carotid body in the rat30 March 2004 | The Journal of Physiology, Vol. 556, No. 1Patch clamp study of mouse glomus cells using a whole carotid bodyNeuroscience Letters, Vol. 357, No. 2Attenuated outward potassium currents in carotid body glomus cells of heart failure rabbit: involvement of nitric oxide18 February 2004 | The Journal of Physiology, Vol. 555, No. 1Effects of reducing agents on glutathione metabolism and the function of carotid body chemoreceptor cellsBiological Chemistry, Vol. 385, No. 3-4Biophysical properties and metabolic regulation of a TASK-like potassium channel in rat carotid body type 1 cellsBeatrice A. Williams, and Keith J. Buckler1 January 2004 | American Journal of Physiology-Lung Cellular and Molecular Physiology, Vol. 286, No. 1Acetylcholine release from the carotid body by hypoxia: evidence for the involvement of autoinhibitory receptorsDong-Kyu Kim, Nanduri R. Prabhakar, and Ganesh K. Kumar1 January 2004 | Journal of Applied Physiology, Vol. 96, No. 1Peripheral chemoreceptors in health and diseaseNanduri R. Prabhakar, and Ying-Jie Peng1 January 2004 | Journal of Applied Physiology, Vol. 96, No. 1Autonomic microganglion cells: a source of acetylcholine in the rat carotid bodyEstelle B. Gauda, Reed Cooper, Shereé M. Johnson, Gabrielle L. McLemore, and Cathleen Marshall1 January 2004 | Journal of Applied Physiology, Vol. 96, No. 1Assessment of Oxygen Sensing by Model Airway and Arterial ChemoreceptorsRole of Glutathione Redox State in Oxygen Sensing by Carotid Body Chemoreceptor CellsEffects of hypoxia and putative transmitters on [Ca2+]i of rat glomus cellsBrain Research, Vol. 995, No. 2Identification of M1 and M2 muscarinic acetylcholine receptors in the cat carotid body chemosensory systemNeuroscience, Vol. 128, No. 3Interactions of chemostimuli at the single cell level: studies in a model system17 December 2003 | Experimental Physiology, Vol. 89, No. 1ATP is a key mediator of central and peripheral chemosensory transduction17 December 2003 | Experimental Physiology, Vol. 89, No. 1Ventilatory responses and carotid body function in adult rats perinatally exposed to hyperoxia10 December 2003 | The Journal of Physiology, Vol. 554, No. 1GABAB receptor activation augments TASK-1 in MAH cells and mediates autoreceptor feedback during hypoxiaBiochemical and Biophysical Research Communications, Vol. 312, No. 2On the association of succinate dehydrogenase mutations with hereditary paragangliomaTrends in Endocrinology & Metabolism, Vol. 14, No. 10GABA Mediates Autoreceptor Feedback Inhibition in the Rat Carotid Body Via Presynaptic GABA B Receptors and TASK-116 July 2004 | The Journal of Physiology, Vol. 553, No. 1ACh and ATP mediate excitatory transmission in cat carotid identified chemoreceptor units in vitroBrain Research, Vol. 988, No. 1-2CO2/H+ sensing: peripheral and central chemoreceptionThe International Journal of Biochemistry & Cell Biology, Vol. 35, No. 10Distribution of transient receptor potential channels in the rat carotid chemosensory pathway29 July 2003 | The Journal of Comparative Neurology, Vol. 464, No. 3Adult carotid chemoafferent responses to hypoxia after 1, 2, and 4 wk of postnatal hyperoxiaG. E. Bisgard, E. B. Olson, Z.-Y. Wang, R. W. Bavis, D. D. Fuller, and G. S. Mitchell1 September 2003 | Journal of Applied Physiology, Vol. 95, No. 3Catecholamine release from isolated sensory neurons of cat petrosal ganglia in tissue cultureBrain Research, Vol. 984, No. 1-2Human skeletal muscle sympathetic nerve activity, heart rate and limb haemodynamics with reduced blood oxygenation and exercise1 September 2003 | The Journal of Physiology, Vol. 551, No. 2Neuroepithelial cells and associated innervation of the zebrafish gill: A confocal immunofluorescence study23 April 2003 | The Journal of Comparative Neurology, Vol. 461, No. 1Characterization of nicotinic acetylcholine receptors in cultured arterial chemoreceptor cells of the catBrain Research, Vol. 974, No. 1-2Renin–angiotensin system in the carotid bodyThe International Journal of Biochemistry & Cell Biology, Vol. 35, No. 6Dopaminergic excitation of the goat carotid body is mediated by the serotonin type 3 receptor subtypeRespiratory Physiology & Neurobiology, Vol. 136, No. 1ATP Triggers Intracellular Ca 2+ Release in Type II Cells of the Rat Carotid Body1 June 2003 | The Journal of Physiology, Vol. 549, No. 3Chronic hypoxia activates a local angiotensin-generating system in rat carotid bodyMolecular and Cellular Endocrinology, Vol. 203, No. 1-2Dopaminergic mechanisms of neural plasticity in respiratory control: transgenic approachesRespiratory Physiology & Neurobiology, Vol. 135, No. 2-3Neuronal growth factors and development of respiratory controlRespiratory Physiology & Neurobiology, Vol. 135, No. 2-3Peripheral O2 chemoreceptors mediate humoral catecholamine secretion from fish chromaffin cellsStephen G. Reid, and Steve F. Perry1 April 2003 | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Vol. 284, No. 4Structural and functional differences of the carotid body between DBA/2J and A/J strains of miceShigeki Yamaguchi, Alexander Balbir, Brian Schofield, Judith Coram, Clarke G. Tankersley, Robert S. Fitzgerald, Christopher P. O'Donnell, and Machiko Shirahata1 April 2003 | Journal of Applied Physiology, Vol. 94, No. 4Effect of domperidone on ventilation and polycythemia after 5 weeks of chronic hypoxia in ratsRespiratory Physiology & Neurobiology, Vol. 135, No. 1Dopamine inhibits ATP-induced responses in the cat petrosal ganglion in vitroBrain Research, Vol. 966, No. 2Carotid sinus nerve chemosensory response to dopamine and acetylcholine in catecholamine depleted catsRespiratory Physiology & Neurobiology, Vol. 134, No. 1Inhibitory effects of NO on carotid body: contribution of neural and endothelial nitric oxide synthase isoformsViviana Valdés, Matías Mosqueira, Sergio Rey, Rodrigo Del Rio, and Rodrigo Iturriaga1 January 2003 | American Journal of Physiology-Lung Cellular and Molecular Physiology, Vol. 284, No. 1Atrial natriuretic peptide stimulates cat carotid body chemoreceptors in vivoComparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, Vol. 134, No. 1Effects of osmotic changes on the chemoreceptor cell of rat carotid body1 January 2003 | The Journal of Physiology, Vol. 546, No. 2Co-expression of NGF and Its High-affinity Receptor TakA in the Rat Carotid Body Chief CellsACTA HISTOCHEMICA ET CYTOCHEMICA, Vol. 36, No. 4Chemoreceptor activity is normal in mice lacking the NK1 receptor11 December 2002 | European Journal of Neuroscience, Vol. 16, No. 11Dopamine Modulates Synaptic Transmission in the Nucleus of the Solitary TractDavid D. Kline, Kristin N. Takacs, Eckhard Ficker, and Diana L. Kunze1 November 2002 | Journal of Neurophysiology, Vol. 88, No. 5Gene expression in peripheral arterial chemoreceptors16 October 2002 | Microscopy Research and Technique, Vol. 59, No. 3Chronic hypoxia-induced morphological and neurochemical changes in the carotid body16 October 2002 | Microscopy Research and Technique, Vol. 59, No. 3Regulation of gene expression for neurotransmitters during adaptation to hypoxia in oxygen-sensitive neuroendocrine cells16 October 2002 | Microscopy Research and Technique, Vol. 59, No. 3Carotid body and glomus cells distributed in the wall of the common carotid artery in the bird16 October 2002 | Microscopy Research and Technique, Vol. 59, No. 3Carotid body chemoreceptors in dissociated cell culture16 October 2002 | Microscopy Research and Technique, Vol. 59, No. 3Antioxidants prevent depression of the acute hypoxic ventilatory response by subanaesthetic halothane in men1 November 2002 | The Journal of Physiology, Vol. 544, No. 3A Possible Dual Site of Action for Carbon Monoxide‐Mediated Chemoexcitation in the Rat Carotid Body1 September 2002 | The Journal of Physiology, Vol. 543, No. 3Chronic hypoxia upregulates connexin43 expression in rat carotid body and petrosal ganglionJ. Chen, L. He, B. Dinger, L. Stensaas, and S. Fidone1 April 2002 | Journal of Applied Physiology, Vol. 92, No. 4Dopaminergic metabolism in carotid bodies and high-altitude acclimatization in female ratsVincent Joseph, Jorge Soliz, Ruddy Soria, Jacqueline Pequignot, Roland Favier, Hilde Spielvogel, and Jean Marc Pequignot1 March 2002 | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Vol. 282, No. 3Central dopamine modulates anapyrexia but not hyperventilation induced by hypoxiaRenata C. H. Barros, and Luiz G. S. Branco1 March 2002 | Journal of Applied Physiology, Vol. 92, No. 3Characteristics of carotid body chemosensitivity in NADPH oxidase-deficient miceL. He, J. Chen, B. Dinger, K. Sanders, K. Sundar, J. Hoidal, and S. Fidone1 January 2002 | American Journal of Physiology-Cell Physiology, Vol. 282, No. 1Reduced to oxidized glutathione ratios and oxygen sensing in calf and rabbit carotid body chemoreceptor cells1 November 2001 | The Journal of Physiology, Vol. 537, No. 1Neuroepithelial bodies in mammalian lung express functional serotonin type 3 receptorX. W. Fu*, D. Wang*, J. Pan, S. M. Farragher, V. Wong, and E. Cutz1 October 2001 | American Journal of Physiology-Lung Cellular and Molecular Physiology, Vol. 281, No. 4Basic FGF localization in rat carotid body: paracrine role in O2-chemoreceptor survivalNeuroreport, Vol. 12, No. 15O 2 Modulates Large-Conductance Ca 2+ -Dependent K + Channels of Rat Chemoreceptor Cells by a Membrane-Restricted and CO-Sensitive MechanismCirculation Research, Vol. 89, No. 5A pH‐sensitive chloride current in the chemoreceptor cell of rat carotid body1 August 2001 | The Journal of Physiology, Vol. 535, No. 1A standing Na+ conductance in rat carotid body type I cellsNeuroreport, Vol. 12, No. 7Barium-stimulated chemosensory activity may not reflect inhibition of background voltage-insensitive K+ channels in the rat carotid bodyBrain Research, Vol. 897, No. 1-2Dual effects of nitric oxide on cat carotid body chemoreceptionRodrigo Iturriaga, Sandra Villanueva, and Matias Mosqueira1 September 2000 | Journal of Applied Physiology, Vol. 89, No. 3Ventilatory responses to acute and chronic hypoxia in mice: effects of dopamine D2 rece
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