Suzuki–Miyaura Coupling Reaction by Pd II ‐Catalyzed Aromatic CH Bond Activation Directed by an N ‐Alkyl Acetamino Group
2007; Wiley; Volume: 46; Issue: 29 Linguagem: Inglês
10.1002/anie.200700590
ISSN1521-3773
AutoresZhang‐Jie Shi, Bi‐Jie Li, Xiaobing Wan, Jiang Cheng, Fang Zhao, Bin Cao, Changming Qin, Yang Wang,
Tópico(s)Cyclopropane Reaction Mechanisms
ResumoA seamless join: An efficient method to construct a C(sp2)C(sp2) bond has been developed by using a Suzuki–Miyaura-type coupling of N-alkyl acetanilides with boronic acids. The reaction was catalyzed by a PdII species and the CH bond activation was directed by the acetamino group (see scheme). This reaction offers a halogen-free method to construct complicated structures.
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