Description of a 23.9-Kilobase Chromosomal Deletion Containing a Region Encoding fsr Genes Which Mainly Determines the Gelatinase-Negative Phenotype of Clinical Isolates of Enterococcus faecalis in Urine
2002; American Society for Microbiology; Volume: 68; Issue: 6 Linguagem: Inglês
10.1128/aem.68.6.3152-3155.2002
ISSN1098-5336
AutoresJiro Nakayama, Reiko Kariyama, Hiromi Kumon,
Tópico(s)Infective Endocarditis Diagnosis and Management
ResumoABSTRACT Expression of virulence-related extracellular proteases, gelatinase, and serine protease of Enterococcus faecalis is regulated by a quorum-sensing system encoded by the fsr gene cluster. In this study, a 23.9-kb chromosomal deletion containing the fsr gene cluster region was found to be present in the majority (79%) of gelatinase-negative clinical isolates of E. faecalis from urine.
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