Inhibition of growth of the dimorphic fungus Paracoccidioides brasiliensis by ajoene
1989; American Society for Microbiology; Volume: 33; Issue: 9 Linguagem: Inglês
10.1128/aac.33.9.1641
ISSN1098-6596
AutoresGioconda San-Blas, Felipe San-Blas, Francisco Javier Martín Gil, Leonardo Mariño, Rafael Apitz‐Castro,
Tópico(s)Phytochemical compounds biological activities
ResumoAjoene, a garlic-derived compound that prevents platelet activation, inhibited the growth of Paracoccidioides brasiliensis, a fungal pathogen for humans, by affecting the integrity of the fungal cytoplasmic membrane. This action may be the basis for the study of ajoene as a possible specific antifungal drug.
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