A Diagram for Interpretation of Acid-Base Changes in Hypercapnia Due to Pulmonary Insufficiency
1965; Taylor & Francis; Volume: 17; Issue: 5 Linguagem: Inglês
10.1080/00365516509075368
ISSN1502-7686
Autores Tópico(s)Respiratory Support and Mechanisms
Resumo(Received for publication May 17, l%5) In recent years there has been an increasing interest in the processes in the body behind the acid-base disturbances observed during hypercapnia. Brackett, Cohen & Schwartz (1965) have shown the effect of increasing degrees of acute hypercapnia in normal man. Refsum has shown the usual or normal” acid-base balance at increasing degrees of chronic hypercapnia in patients with pulmonary insufficiency, after achievement of probably maximal renal compensation, but uncomplicated by major metabolic acid-base disturbances (Refsum 1960, 1964, 1965), and has studied the acid-base changes during recovery from chronic hypercapnia in the same type of patients (Refsum 1961, 1962, 1965). Robin (1963) has demonstrated the frequent occurrence of superimposed metabolic alkalosis in chronic hypercapnia, and Kassirer, Berkman, Lawrenz & Schwartz (1965) have emphasized the critical role of chloride in correction of post-hypercapneic
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