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Prophylactic use of mitomycin-C in the management of a buttonholed LASIK flap

2003; Lippincott Williams & Wilkins; Volume: 29; Issue: 2 Linguagem: Inglês

10.1016/s0886-3350(02)01434-7

1873-4502

Howard A. Lane, Jerome A. Swale, Parag A. Majmudar,

Glaucoma and retinal disorders

We report a case in which prophylactic mitomycin-C (MMC) was used to prevent haze and scarring after photorefractive keratectomy (PRK) in an eye with a previous laser in situ keratomileusis flap buttonhole. During the patient's primary procedure, a 3.5 mm central buttonhole was created during the microkeratome pass. The flap was repositioned without laser application. Follow-up examinations revealed a moderate central buttonhole scar. Twelve months later, the patient had PRK with adjunctive MMC 0.02% application in the eye. At the 1-year examination, the uncorrected visual acuity was 20/20 and the cornea was clear with no evidence of scarring or haze.