Portal de Periódicos da CAPES

Endothelial nitric oxide synthase activation leads to dilatory H2O2 production in mouse cerebral arteries

2006; Oxford University Press; Volume: 73; Issue: 1 Linguagem: Inglês

10.1016/j.cardiores.2006.10.005

1755-3245

Annick Drouin, Nathalie Thorin‐Trescases, E HAMEL, John R. Falck, Éric Thorin,

Electron Spin Resonance Studies

Objective: Hydrogen peroxide (H2O2) produced by the vascular endothelium is a signaling molecule regulating vascular tone. We hypothesized that H2O2 derived from eNOS activity could play a physiological role in endothelium-dependent dilation of mouse cerebral arteries.