Artigo Acesso aberto Revisado por pares

Population-Representative Incidence of Drug-Induced Acute Liver Failure Based on an Analysis of an Integrated Health Care System

2015; Elsevier BV; Volume: 148; Issue: 7 Linguagem: Inglês

10.1053/j.gastro.2015.02.050

ISSN

1528-0012

Autores

David S. Goldberg, Kimberly A. Forde, Dena M. Carbonari, James D. Lewis, Kimberly B.F. Leidl, K. Rajender Reddy, Kevin Haynes, Jason Roy, Daohang Sha, Amy R. Marks, Jennifer L. Schneider, Brian L. Strom, Douglas A. Corley, Vincent Lo Re,

Tópico(s)

Pharmacological Effects and Toxicity Studies

Resumo

Medications are a major cause of acute liver failure (ALF) in the United States, but no population-based studies have evaluated the incidence of ALF from drug-induced liver injury. We aimed to determine the incidence and outcomes of drug-induced ALF in an integrated health care system that approximates a population-based cohort.

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