Portal de Periódicos da CAPES

dbVar and DGVa: public archives for genomic structural variation

2012; Oxford University Press; Volume: 41; Issue: D1 Linguagem: Inglês

10.1093/nar/gks1213

1362-4962

Ilkka Lappalainen, John Lopez, Lisa Skipper, Timothy Hefferon, Dylan Spalding, John Garner, Chao Chen, Michael E. Maguire, Matt Corbett, George Zhou, Justin Paschall, Victor Ananiev, Paul Flicek, Deanna M. Church,

Genomic variations and chromosomal abnormalities

Much has changed in the last two years at DGVa (http://www.ebi.ac.uk/dgva) and dbVar (http://www.ncbi.nlm.nih.gov/dbvar). We are now processing direct submissions rather than only curating data from the literature and our joint study catalog includes data from over 100 studies in 11 organisms. Studies from human dominate with data from control and case populations, tumor samples as well as three large curated studies derived from multiple sources. During the processing of these data, we have made improvements to our data model, submission process and data representation. Additionally, we have made significant improvements in providing access to these data via web and FTP interfaces.