Artigo Acesso aberto Revisado por pares

Sequence of pNL194, a 79.3-Kilobase IncN Plasmid Carrying the bla VIM-1 Metallo-β-Lactamase Gene in Klebsiella pneumoniae

2010; American Society for Microbiology; Volume: 54; Issue: 10 Linguagem: Inglês

10.1128/aac.00665-10

ISSN

1098-6596

Autores

Vivì Miriagou, Costas C. Papagiannitsis, Stathis D. Kotsakis, A. Loli, Εva Tzelepi, N.J. Legakis, L. S. Tzouvelekis,

Tópico(s)

Bacterial biofilms and quorum sensing

Resumo

The nucleotide sequence of pNL194, a VIM-1-encoding plasmid, is described in this study. pNL194 (79,307 bp) comprised an IncN-characteristic segment (38,940 bp) and a mosaic structure (40,367 bp) including bla(VIM-1), aacA7, aadA1, aadA2, dfrA1, dfrA12, aphA1, strA, strB, and sul1. Tn1000 or Tn5501 insertion within fipA probably facilitated recruitment of additional mobile elements carrying resistance genes.

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