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The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria

2010; Oxford University Press; Volume: 65; Issue: 9 Linguagem: Inglês

10.1093/jac/dkq220

1460-2091

Maria Pränting, Camilla Lööv, Robert Burman, Ulf Göransson, Dan I. Andersson,

Antimicrobial Peptides and Activities

ObjectivesTo determine the antibacterial activity of small cyclic plant proteins, i.e. cyclotides, and the importance of the surface exposed charged residues for activity.