Portal de Periódicos da CAPES

Rational design of small molecules as vaccine adjuvants

2014; American Association for the Advancement of Science; Volume: 6; Issue: 263 Linguagem: Inglês

10.1126/scitranslmed.3009980

1946-6242

Tom Wu, Manmohan Singh, Andrew T. Miller, Ennio De Gregorio, Francesco Doro, Ugo D’Oro, David Skibinski, M. Lamine Mbow, Simone Bufali, Ann Herman, Alex Cortez, Yongkai Li, Bishnu P. Nayak, Elaine Tritto, Christophe Filippi, Gillis R. Otten, Luis A. Brito, Elisabetta Monaci, Chun Li, Susanna Aprea, Sara Valentini, Samuele Calabrό, Donatello Laera, Brunella Brunelli, Elena Caproni, Padma Malyala, Rekha G. Panchal, Travis K. Warren, Sina Bavari, Derek T. O’Hagan, M. Cooke, Nicholas M. Valiante,

Monoclonal and Polyclonal Antibodies Research

Small-molecule immune potentiators can be engineered to be potent adjuvants with localized innate immune activation and short in vivo residence times.