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A Pocket‐Sized Convective PCR Thermocycler

2007; Wiley; Volume: 46; Issue: 23 Linguagem: Inglês

10.1002/anie.200700306

1521-3773

Nitin Agrawal, Yassin A. Hassan, Victor M. Ugaz,

Innovative Microfluidic and Catalytic Techniques Innovation

Is that a PCR in your pocket? An innovative thermocycling system is presented that harnesses natural convection to perform rapid multiplex and long-target DNA amplification by the polymerase chain reaction (PCR). The design is inherently simple and consumes minimal electrical power, enabling a pocket-sized battery-powered device to be constructed at a cost of approximately US$10. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z700306_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.