Artigo Acesso aberto Produção Nacional Revisado por pares

The prevalence of human cytomegalovirus DNA in gliomas of Brazilian patients

2012; Instituto Oswaldo Cruz, Ministério da Saúde; Volume: 107; Issue: 7 Linguagem: Inglês

10.1590/s0074-02762012000700020

ISSN

1678-8060

Autores

Renata F. Fonseca, Márcia Tie Kawamura, José Antônio de Oliveira, Anselmo Teixeira, Gilda Alves, María da Gloria Carvalho,

Tópico(s)

Toxoplasma gondii Research Studies

Resumo

Members of the Herpesviridae family have been implicated in a number of tumours in humans. At least 75% of the human population has had contact with cytomegalovirus (HCMV). In this work, we screened 75 Brazilian glioma biopsies for the presence of HCMV DNA sequences. HCMV DNA was detected in 36% (27/75) of the biopsies. It is possible that HCMV could be a co-factor in the evolution of brain tumours.

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