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Single cells from human primary colorectal tumors exhibit polyfunctional heterogeneity in secretions of ELR+ CXC chemokines

2013; Oxford University Press; Volume: 5; Issue: 10 Linguagem: Inglês

10.1039/c3ib40059j

1757-9708

Viktor A. Adalsteinsson, Narmin Tahirova, Naren Tallapragada, Xiaosai Yao, Liam Campion, Alessandro Angelini, Thomas B. Douce, Cindy Y. Huang, Brittany A. Bowman, Christina A. Williamson, Douglas S. Kwon, K. Dane Wittrup, J. Christopher Love,

T-cell and B-cell Immunology

Journal Article Single cells from human primary colorectal tumors exhibit polyfunctional heterogeneity in secretions of ELR+ CXC chemokines Get access Viktor A. Adalsteinsson, Viktor A. Adalsteinsson Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. Tel: +1-617-324-2300Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, Massachusetts 02139, USAThe Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA Search for other works by this author on: Oxford Academic Google Scholar Narmin Tahirova, Narmin Tahirova Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, Massachusetts 02139, USAThe Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA Search for other works by this author on: Oxford Academic Google Scholar Naren Tallapragada, Naren Tallapragada Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, Massachusetts 02139, USADepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA Search for other works by this author on: Oxford Academic Google Scholar Xiaosai Yao, Xiaosai Yao Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, Massachusetts 02139, USADepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA Search for other works by this author on: Oxford Academic Google Scholar Liam Campion, Liam Campion Janssen Pharmaceuticals, Spring House, Pennsylvania 19477, USA Search for other works by this author on: Oxford Academic Google Scholar Alessandro Angelini, Alessandro Angelini Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, Massachusetts 02139, USA Search for other works by this author on: Oxford Academic Google Scholar Thomas B. Douce, Thomas B. Douce Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, Massachusetts 02139, USA Search for other works by this author on: Oxford Academic Google Scholar Cindy Huang, Cindy Huang Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. Tel: +1-617-324-2300Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, Massachusetts 02139, USA Search for other works by this author on: Oxford Academic Google Scholar Brittany Bowman, Brittany Bowman The Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts 02139, USA Search for other works by this author on: Oxford Academic Google Scholar Christina A. Williamson, Christina A. Williamson Department of Thoracic and Cardiovascular Surgery, Lahey Clinic, Burlington, Massachusetts 01805, USA Search for other works by this author on: Oxford Academic Google Scholar ... Show more Douglas S. Kwon, Douglas S. Kwon The Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts 02139, USA Search for other works by this author on: Oxford Academic Google Scholar K. Dane Wittrup, K. Dane Wittrup Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. Tel: +1-617-324-2300Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, Massachusetts 02139, USADepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA Search for other works by this author on: Oxford Academic Google Scholar J. Christopher Love J. Christopher Love Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. Tel: +1-617-324-2300Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, Massachusetts 02139, USAThe Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USAThe Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts 02139, USA E-mail: clove@mit.edu Search for other works by this author on: Oxford Academic Google Scholar Integrative Biology, Volume 5, Issue 10, October 2013, Pages 1272–1281, https://doi.org/10.1039/c3ib40059j Published: 30 August 2013 Article history Received: 20 March 2013 Accepted: 08 August 2013 Published: 30 August 2013