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Structural comparison of several actin-binding macromolecules.

1980; Rockefeller University Press; Volume: 85; Issue: 2 Linguagem: Inglês

10.1083/jcb.85.2.489

1540-8140

Jonathan M. Tyler, James Michael Anderson, Daniel Branton,

Lipid Membrane Structure and Behavior

The cytoskeletal components, macrophage actin-binding protein and filamin, were dried from glycerol and examined by low-angle rotary shadowing electron microscopy. Both are elongate, flexible molecules whose general morphologi is similar to that of erythrocyte spectrin. Neither actin-binding protein nor filamin binds to spectrin-depleted erythrocyte membranes.